Frederick Unverzagt, Ph.D.

Frederick W. Unverzagt, Ph.D.
Professor of Clinical Psychology in Clinical Psychiatry
Professor of Clinical Medical and Molecular Genetics


Personal Statement 

My research focuses on cognition in age-related diseases particularly Alzheimer disease.  One strong theme in my research is the epidemiology of Alzheimer disease.  I also investigate the heterogeneity of Mild Cognitive Impairment and conduct randomized clinical trials of the effectiveness of non-pharmacologic interventions to improve cognition and delay onset of dementia.  In addition to research, I actively promote the professional practice of psychology and have been elected to the boards of the Indiana Psychological Association, the American Board of Clinical Neuropsychology (the primary board certification organization in neuropsychology), and the Association of Postdoctoral Programs in Clinical Neuropsychology (a membership organization of residency training programs).



Undergraduate: Southern Illinois University at Carbondale

Graduate School: Southern Illinois University at Carbondale

Internship: Milwaukee County Medical Center

Fellowship: Medical College of Wisconsin

Board Certifications/Certifications:

American Board of Professional Psychology-Clinical Neuropsychology

Current Academic Interests 

Teaching: I am the Residency Training Director for the Clinical Neuropsychology Residency, an APPCN-affiliated, two-year residency in Clinical Neuropsychology.   I also provide lectures on neuropsychological assessment, functional neuroanatomy, neurobiology of memory, dementia, and Alzheimer disease to psychology graduate students and medical students, interns, and residents.

Clinical: I founded the Neuropsychology Clinic in Psychiatry at Indiana University School of Medicine and provide assessment and diagnosis of the full spectrum of neurobehavioral pathologies including:  Alzheimer disease, Lewy Body disease, fronto-temporal disease, stroke, multiple sclerosis, brain tumor, traumatic brain injury, and occupational exposure.   I also perform independent medical examinations for insurance companies and attorneys.

Research My research interests are focused on the clinical assessment of memory loss and cognitive impairment associated with neurodegenerative disease and breast cancer. I developed a brief, reliable, and valid telephone-based cognitive assessment battery for use in breast cancer research, the Indiana University Telephone-based Assessment of Neuropsychological Status (IU-TBANS). I have also developed and adapted cognitive assessments for use in cross-cultural studies in Nigeria, Kenya, Jamaica, and China. I am site PI for one of the largest randomized, controlled trials of a cognitive intervention ever undertaken, the ACTIVE (Advanced Cognitive Training for Independent Vital Elderly) study.

Recent Publications

Unverzagt FW, Guey LT, Jones RN, Marsiske M, King JW, Wadley VG, Crowe M, Rebok GW, Tennstedt SL. (2012).  ACTIVE cognitive training and rates of incident dementia.  Journal of the International Neuropsychological Society, 18, 1-9.

Unverzagt FW, McClure LA, Wadley VG, Jenny NS, Go RC, Cushman M, Kissela BM, Kelley BJ, Kennedy R, Moy CS, Howard V, & Howard G.  (2011).  Vascular risk factors and cognitive impairment in a stroke-free cohort.  Neurology, 77, 1729-1736.

Unverzagt FW,  Ogunniyi A, Taler V, Gao S, Lane KA, Baiyewu O, Gureje O, Smith-Gamble V, Hake A, Hendrie HC & Hall KS. (2011).  Incidence and risk factors for cognitive impairment no dementia and mild cognitive impairment in African Americans.  Alzheimer Disease and Associated Disorders, 25, 4-10.

Unverzagt FW, Smith DM, Rebok GW, Marsiske M, Morris JN, Jones, R, Willis SL, Ball K, King JW, Koepke KM, Stoddard A, & Tennstedt SL  (2009). Cognitive training in older adults:  Lessons from the ACTIVE study.  Current Alzheimer Research, 6, 375-383.


Frederick Unverzagt, Ph.D.

Goodman Hall
355 W. 16th Street
Suite 2800
Indianapolis, IN 46202
(317) 963-7301

Department of Psychiatry | 355 W. 16th St., Suite 4800 | Indianapolis, IN 46202 | Ph: (317) 963-7316 | Fax: (317) 963-7313